ACCORD: microvascular outcomes
http://general-medicine.jwatch.org/cgi/content/full/2010/1230/3?q=topic_diabetes 老年糖尿病患者,嚴格血糖控制,對ESRD, retinopathy沒有用,neuropathy有一點點用 血脂控制(加上fenofibrate)也沒有滿意的答案 唯一一個明確的答案是BP control SBP 130mmHg 即可 ACCORD: Microvascular Outcomes In older diabetic patients, clinical microvascular endpoints were unaffected by tight glycemic control. In the landmark ACCORD trial, older patients with longstanding type 2 diabetes were randomized to various intensities of glycemic control, blood pressure (BP) control, and lipid management. The first round of published results dealt with so-called "macrovascular outcomes" — myocardial infarction, stroke, and cardiovascular death (JW Gen Med Jun 6 2008, JW Cardiol Mar 14 2010, and JW Cardiol Mar 14 2010; also JW Gen Med Dec 30 2010). In 2010, data on microvascular outcomes were published. In the glycemic-control arm of the study, patients were randomized to intensive or standard treatment, which resulted in mean glycosylated hemoglobin (HbA1c) levels...