TB新藥，診斷方法，和疫苗

每次去衛生所講都講個案，個案講來講去就是社會因素不聽話，不然就是太老，身體太差，副作用一堆，大概就是這樣，老病沒有新把戲
為了不被人家笑是騙錢
把東西看了一下

TAG report 2010(treatment action group)

對於HIV, viral hepatitis, TB 最近的pipeline做整理
沒有看得很清楚，不過似乎有很多TB vaccine的經費(61%)，自2008年後，是由BMGF(Bill Gates)的基金會捐助的，所以2008年後TB vaccine的研究突飛猛進，有錢好辦事

https://docs.google.com/fileview?id=0B278nGJMQBk7MzlhMzk5ZDgtZWQ0Yi00NWMyLTk1MDMtMzAyZjNmMzM2ODYw&hl=zh_TW

2009 結核病年報

https://docs.google.com/fileview?id=0B278nGJMQBk7YzZiM2I4MTAtYWE3ZC00ZjZlLTk3NDgtNGQwYjljNTkxMmMz&hl=zh_TW

荷蘭利用RFLP做smear negative TB和smear positive TB的比較，smear negative TB造成的TB infection佔 12.6%, 傳染力是smear positive TB的24%

https://docs.google.com/leaf?id=0B278nGJMQBk7MjQ0NjljNDgtNzRkNy00NjA4LTg4MmQtNmNjOTViOGMzNWZi&hl=zh_TW

TB pleurisy 利用 sputum induction, 仍有一半的病人sputum TB culture 會陽性

https://docs.google.com/fileview?id=0B278nGJMQBk7NmU2NGExZTUtNmEwMy00MjRkLWEwY2ItMDgxZmE3NWNjNjdh&hl=zh_TW

https://docs.google.com/present/edit?id=0AW78nGJMQBk7ZGc1d3FjYmpfMjQ5cDlyNnBiY20&hl=zh_TW

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這個網誌中的熱門文章

即便是用IGRA, 有時也要等大於三個月才能決定TB contact

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接觸TB後，TST大抵上2-12週轉陽，IGRA大抵上6-10週，但IGRA可以長到3個月以上 TB Tests Can Have a Lengthy Window Period Two studies suggest that interferon- release assay conversion sometimes occurs more than 3 months after exposure to active tuberculosis. Increasingly, interferon- release assays (IGRAs) are being used for diagnosing latent tuberculosis (TB). Although the tuberculin skin test (TST) traditionally used for this purpose converts to positive within 2 to 12 weeks after an individual is exposed to someone with active TB, the interval for IGRA conversion has remained unclear. Current guidelines recommend repeating an initially negative IGRA after 6 to 10 weeks, but this recommendation is not based on controlled studies. Two recent investigations address this issue. Anibarro and colleagues conducted a longitudinal prospective analysis among contacts of TB patients in Spain. The 152 contacts received a TST and an IGRA at first visit; for individuals with negative or conflicting results, t
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TG無用論，不用吃fenofibrate了，除非> 500mg/dl

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不用管TG levels，除非高到>500 好好吃東西，好好運動，比吃藥重要!! Don't Miss the New AHA Recommendations on Triglycerides A new scientific statement raises the threshold for pharmacologic treatment of hypertriglyceridemia. The following was published as a "Voices" blog on CardioExchange , an online forum for cardiology news and discussion. The blog prompted a lively conversation, which you can access and join by registering for CardioExchange. I've been surprised at the lack of fanfare surrounding the American Heart Association's recently published scientific statement on triglycerides and cardiovascular disease (CVD). The attention it did receive focused on the lower fasting triglyceride level that is now considered optimal: <100 mg/dL. In my opinion, the real headline was the committee's important statements in support of less drug treatment — in particular, the recommendation for a substantial increase in the triglyceride level that should trigger consideratio
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